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Impact of cage density on body weight, organ mass, cortisol concentration, and blood metabolites in Wistar albino rats     
Yazarlar (2)
Doç. Dr. Buket BOĞA KURU Doç. Dr. Buket BOĞA KURU
Kafkas Üniversitesi, Türkiye
Doç. Dr. Mustafa MAKAV Doç. Dr. Mustafa MAKAV
Kafkas Üniversitesi, Türkiye
Devamını Göster
Özet
This study investigated the effects of different cage density and gender on growth performance, live weight gain, organ weight, cortisol concentration, and some biochemical parameters in growing Wistar rats. Twenty four, 6 weeks old rats (12 males, 12 females) were followed up to 15 weeks of age. The male and female control groups (MC and FC) were kept in cages at normal density, while the high cage density groups (MHD and FHD) were housed in cages at twice the density. Blood was collected and organs were weighed at 15 weeks of age. Live weight was significantly affected by both cage density and gender in male and female rats. Live weight was 7% lower in the MHD group than in the MC group in males and 9.5% lower in females. Heart, spleen, and total intestinal weights were lower in the MHD group than in the MC group in males. Serum cortisol, glucose, triglyceride, alanine aminotransferase, aspartate aminotransferase, and total protein concentrations were different between both MC and MHD and FC and FHD. Serum low-density lipoprotein and albumin concentrations were higher in MHD than in MC. In conclusion, high cage density negatively affects live weight, organ weights, and some biochemical parameters in growing Wistar rats
Anahtar Kelimeler
Housing density | Growth performance | Organ weight | Gender | Stress
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Indian Journal of Experimental Biology
Dergi ISSN 0019-5189 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2025
Cilt No 63
Sayı 1
Sayfalar 103 / 111
Doi Numarası 10.56042/ijeb.v63i01.10615
Makale Linki https://doi.org/10.56042/ijeb.v63i01.10615