Synthesis and Antioxidant and Antibacterial Activities of Novel 4-({[3-Alkyl(aryl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl]imino}-methyl)phenyl 4-Nitrobenzoate Derivatives
Yazarlar (9)
Prof. Dr. Muzaffer ALKAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
Doç. Dr. Sevda MANAP Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gül ÖZDEMİR TORAMAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Murat BEYTUR Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fevzi AYTEMİZ Kafkas Üniversitesi, Türkiye
Nahsen Şahin
Halil Ağırbaş
Prof. Dr. Özlem Gürsoy Kol Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (Q4)
Dergi ISSN 1070-4280 Dergi Bilgileri (2023)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 02-2023
Cilt / Sayı / Sayfa 58 / 12 / 1839–1850 DOI 10.1134/S1070428022120132
Makale Linki https://link.springer.com/article/10.1134/S1070428022120132
UAK Araştırma Alanları
Fen Bilimleri ve Matematik
Özet
It is known that acetyl derivatives, Schiff bases, and Mannich bases obtained from 1,2,4-triazol-5-ones have significant antibacterial and antioxidant activities. Herein, 27 new 1,2,4-triazole derivatives were synthesized, and their antioxidant and antibacterial properties were investigated. The metal chelating activity of the synthesized compounds and especially the effect against gram-positive bacteria were found to be significant. The effect against gram-negative strains was also important. Structure determination of the synthesized compounds was performed on the basis of their 1H and 13C NMR, IR, and high-resolution mass spectra.
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