img
img
Effects of hydrogen‐rich water on growth, redox homeostasis and hormonal, histological and immune systems in rats exposed to high cage density stress        
Yazarlar (11)
Dr. Öğr. Üyesi Buket BOĞA KURU Dr. Öğr. Üyesi Buket BOĞA KURU
Kafkas Üniversitesi, Türkiye
Doç. Dr. Mustafa MAKAV Doç. Dr. Mustafa MAKAV
Kafkas Üniversitesi, Türkiye
Doç. Dr. Mushap KURU Doç. Dr. Mushap KURU
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Şükran YEDİEL ARAS Dr. Öğr. Üyesi Şükran YEDİEL ARAS
Kafkas Üniversitesi, Türkiye
Prof. Dr. Ebru KARADAĞ SARI Prof. Dr. Ebru KARADAĞ SARI
Kafkas Üniversitesi, Türkiye
Menekşe Bulut
Iğdır Üniversitesi, Türkiye
Dureyt Veziroğlu
Iğdır Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fikret BEKTAŞOĞLU Dr. Öğr. Üyesi Fikret BEKTAŞOĞLU
Kafkas Üniversitesi, Türkiye
Doç. Dr. Mükremin ÖLMEZ Doç. Dr. Mükremin ÖLMEZ
Kafkas Üniversitesi, Türkiye
Prof. Dr. Turgut KIRMIZIBAYRAK Prof. Dr. Turgut KIRMIZIBAYRAK
Kafkas Üniversitesi, Türkiye
Tyler W. Lebaron
Devamını Göster
Özet
This study investigated the impact of drinking hydrogen-rich water (HRW) on growth performance, organ weights, thiol/disulphide homeostasis, oxidative status and some hormonal, histopathological and immunohistochemical changes in rats fed in a restricted housing environment. The eight groups (each group [male/female] eight rats) comprised two control, two hydrogen, two stress and two stress + hydrogen. All animals were given feed and water ad libitum for 3 months. Control and HRW group rats were calculated according to weight and housed according to the Guide's housing condition. The stress group and stress + HRW group were housed in half the area of the Guide's housing condition according to their weight. The animal's weekly body weights were measured throughout the study. The animals were sacrificed in accordance with ethical rules. Then, biochemical analyses were performed on thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), cortisol, parathyroid hormone (PTH) and calcium (Ca), total thiol (TT), native thiol (NT), disulphide, disulphide/TT × 100, disulphide/NT × 100 and NT/TT × 100, malondialdehyde (MDA) and glutathione (GSH). Haematoxylin staining for histopathological and SOD-2 immunoreactivity was also assessed. Results showed that live weight gain was higher in the HRW groups than in the stress group. Oxidant status in biochemical analyses decreased in the stress + HRW group compared to the stress group. TSH decreased in the stress group. FT4, cortisol and Ca increased in the stress group. The stress-related physiological parameters were reduced in the HRW + stress group compared to the stress group. HRW could be suggested when the organism is found in stressful conditions.
Anahtar Kelimeler
growth performance | hydrogen-rich water | molecular hydrogen | oxidative status | stress
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Veterinary Medicine and Science
Dergi ISSN 2053-1095 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 03-2025
Cilt No 11
Sayı 2
Sayfalar 70305 / 0
Doi Numarası 10.1002/vms3.70305
Makale Linki https://doi.org/10.1002/vms3.70305