Synthesis and Antioxidant and Antibacterial Activities of Novel 4-({[3-Alkyl(aryl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl]imino}­methyl)phenyl 4-Nitrobenzoate Derivatives
Yazarlar (9)
M. Alkan
Kafkas Üniversitesi, Türkiye
H. Yüksek
Kafkas Üniversitesi, Türkiye
S. Manap
Kafkas Üniversitesi, Türkiye
G. Ozdemir
Kafkas Üniversitesi, Türkiye
Doç. Dr. Murat BEYTUR Kafkas Üniversitesi, Türkiye
F. Aytemız
Kafkas Üniversitesi, Türkiye
N. Şahin
Kafkas Üniversitesi, Türkiye
H. Ağirbaş
Kafkas Üniversitesi, Türkiye
O. Gursoy-Kol
Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
Dergi Adı Russian Journal of Organic Chemistry
Dergi ISSN 1070-4280 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler
Makale Dili İngilizce Basım Tarihi 12-2022
Cilt / Sayı / Sayfa 58 / 12 / 1839–1850 DOI 10.1134/S1070428022120132
Makale Linki https://doi.org/10.1134/S1070428022120132
UAK Araştırma Alanları
Eğitim Bilimleri
Özet
It is known that acetyl derivatives, Schiff bases, and Mannich bases obtained from 1,2,4-triazol-5-ones have significant antibacterial and antioxidant activities. Herein, 27 new 1,2,4-triazole derivatives were synthesized, and their antioxidant and antibacterial properties were investigated. The metal chelating activity of the synthesized compounds and especially the effect against gram-positive bacteria were found to be significant. The effect against gram-negative strains was also important. Structure determination of the synthesized compounds was performed on the basis of their 1H and 13C NMR, IR, and high-resolution mass spectra.
Anahtar Kelimeler
1,2,4-triazole derivatives | antibacterial activity | antioxidant activity | Mannich bases | Schiff bases