img
img
Recent advances in quinazolinone derivatives: structure, design and therapeutic potential    
Yazarlar (1)
Doç. Dr. Feyzi Sinan TOKALI Doç. Dr. Feyzi Sinan TOKALI
Kafkas Üniversitesi, Türkiye
Devamını Göster
Özet
Quinazolinones, a prominent class of heterocyclic compounds, have garnered significant attention due to their diverse biological activities and synthetic versatility. Over the past thirty years, extensive research has been conducted to explore their pharmacological potential, making them an essential scaffold in modern medicinal chemistry.This review provides an analysis of the most common synthesis methods employed for the preparation of quinazolinones, highlighting their efficiency and applicability. Furthermore, it presents an in-depth discussion of their broad-spectrum biological activities, including anticancer, antimicrobial, antifungal, anti-inflammatory, anticonvulsant, anti-Alzheimer's, antiparasitic, antioxidant, antidiabetic, and antiviral properties. By summarizing the latest advancements in quinazolinone research, specifically those made in the past five years, this review aims to serve as a valuable resource for researchers, facilitating easy access to recent studies and promoting further advancements in the field.
Anahtar Kelimeler
Quinazolinone | quinazolin-4(3H)-one | biological potential | anticancer | antimicrobial
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Future Medicinal Chemistry
Dergi ISSN 1756-8919 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 05-2025
Cilt No 17
Sayı 9
Sayfalar 1071 / 1091
Doi Numarası 10.1080/17568919.2025.2504327
Makale Linki https://doi.org/10.1080/17568919.2025.2504327
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Recent advances in quinazolinone derivatives: structure, design and therapeutic potential

Paylaş