Investigation of Adenosıne deamıdase (ADA) activity and some biochemical values in lambs with infectious ecthyma symptoms
Yazarlar (6)
S. Kızıltepe
Iğdır Üniversitesi, Türkiye
Iğdır Üniversitesi, Türkiye
C. Okulmus Izmir/Bornova Veterinary Control Institute, Türkiye
R. Akpınar Bee Hospital Laboratory, Türkiye
O. Merhan
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Prof. Dr. Kadir BOZUKLUHAN Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Nüvit COŞKUN Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Arquivo Brasileiro De Medicina Veterinaria E Zootecnia (Q4) | ||
| Dergi ISSN | 0102-0935 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2025 |
| Cilt / Sayı / Sayfa | 77 / 4 / 1–6 | DOI | 10.1590/1678-4162-13399 |
| Makale Linki | www.google.com.tr | ||
| UAK Araştırma Alanları |
Veteriner İç Hastalıkları
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| Özet |
| Understanding the zoonotic risk posed by the orf virus (ORFV), which causes contagious ecthyma in domestic animals, is crucial for both human and animal health. Contagious ecthyma is a highly contagious, zoonotic, viral skin disease that affects sheep, goats, and certain other domestic and wild animals. In this study, serum malondialdehyde (MDA), nitric oxide (NO), reduced glutathione (GSH) concentrations, and adenosine deaminase (ADA) activity were measured in healthy and naturally infected lambs with ecthyma. Compared to healthy lambs, serum MDA (respectively; 2.69±0.4 vs. 4.73±0.24 μmol/L, P<0.001), NO (respectively; 6.12±0.72 vs. 8.32±0.55μmol/L, P<0.05) and ADA (respectively; 7.12±0.60 vs. 21.53±1.82 U/L, P<0.001) concentrations increased, while GSH (respectively; 15.01±1.59vs. 10.05±1.10mg/dL, P<0.05) levels decreased in contagious ecthyma lambs. As a result, it was concluded that oxidative stress developed in lambs infected with contagious ecthyma, ADA enzyme activity increased, and this could be useful for the diagnosis of the disease. |
| Anahtar Kelimeler |
| Adenosine deaminase | ecthyma | lamb | oxidative stress |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 1 |
| Google Scholar | 2 |