| Yazarlar (1) |
Doç. Dr. Hatice Esra DURAN
Kafkas Üniversitesi, Türkiye |
| Özet |
| The discovery of acetylcholinesterase inhibitors is important for the treatment of Alzheimer's disease, which is the most common type of dementia. Due to the side effects of commonly used acetylcholinesterase inhibitors, studies aimed at discovering new inhibitors are increasing. Therefore, in this study, the effects of some benzoquinone derivatives, 1, 4-benzoquinone (1a), 2, 6-dichloro-1, 4 benzoquinone (1b), and 2, 6-dimethyl-1, 4-benzoquinone (1c) on AChE enzyme were investigated. In vitro studies were conducted to understand the possible inhibition mechanism in the interaction of enzyme-benzoquinone compounds, and the effects of these compounds were examined. The quinones examined were found to exhibit effective inhibition of the AChE enzyme. IC50 values were |
| Anahtar Kelimeler |
| Makale Türü |
Özgün Makale
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| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayınlanan tam makale |
| Dergi Adı | German Journal of Pharmaceuticals and Biomaterials |
| Dergi ISSN | 2750-624X |
| Dergi Tarandığı Indeksler | Scilit, Google scholar, crossref, Scribd, cite factor, ResearchBib |
| Makale Dili | Türkçe |
| Basım Tarihi | 05-2025 |
| Cilt No | 4 |
| Sayı | 1 |
| Sayfalar | 3 / 10 |
| Doi Numarası | 10.5530/gjpb.2025.1.2 |
| Makale Linki | https://doi.org/10.5530/gjpb.2025.1.2 |
| Atıf Sayıları |
