Yazarlar (9) |
![]() Kafkas Üniversitesi, Turkey |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Turkey |
![]() Kayseri City Hospital, Turkey |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
Özet |
Hypertension is a common and persistent disorder and mostly causes myocardial structural and functional abnormalities. As a subtype pattern of HT, the reverse-dipper blood pressure (BP) is associated with worse cardiovascular outcomes and early-phase subclinical myocardial damage compared to other patterns. The Left Atrial Coupling Index (LACI) is a novel echocardiographic parameter developed to assess the mechanical function. The aim of this study was to investigate the role of the LACI in predicting the reverse-dipper BP pattern in patients with hypertension. A total of 404 hypertensive patients who underwent 24-hour ambulatory blood pressure monitoring were prospectively enrolled. Patients were classified into dipper, non-dipper, and reverse-dipper groups based on their nocturnal BP profiles. Comprehensive echocardiographic evaluations were performed, and LACI was calculated for each patient. A reverse-dipper BP pattern was observed in 26%(n = 105) of the 404 patients. Those with a reverse-dipper BP pattern exhibited higher mitral E/A ratio, E/Em means, left atrial volume index (LAVI), and LACI, along with lower Em septal, Am lateral mitral, and Am septal values. LACI (OR:3.837, 95% CI: 2.620-5.620, p < 0.001), LAVI, and Am lateral mitral value were found to be independent predictors of the reverse-dipper BP pattern. ROC curve comparison demonstrated that LACI was a better predictor of the reverse-dipper BP pattern than LAVI. Our study demonstrates that LACI, an easily accessible echocardiographic parameter, is a more robust predictor of the reverse-dipper BP pattern compared to traditional echocardiographic markers. |
Anahtar Kelimeler |
Left Atrial Coupling Index | Reverse-dipper Blood Pressure Pattern | 24-hour Ambulatory Blood Pressure Monitoring | Hypertension | Nocturnal Blood Pressure Patterns |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
Dergi Adı | HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION |
Dergi ISSN | 1120-9879 Wos Dergi Scopus Dergi |
Makale Dili | İngilizce |
Basım Tarihi | 07-2025 |
Sayı | 1 |
Doi Numarası | 10.1007/s40292-025-00733-w |