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A Practical Predictor for Identifying Reverse-Dipper Blood Pressure Patterns: Left Atrial Coupling Index    
Yazarlar (9)
Ayca Arslan
Kafkas Üniversitesi, Turkey
Dr. Öğr. Üyesi Doğan İLİŞ Dr. Öğr. Üyesi Doğan İLİŞ
Kafkas Üniversitesi, Türkiye
Doç. Dr. İnanç ARTAÇ Doç. Dr. İnanç ARTAÇ
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Muammer KARAKAYALI Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye
Timor OMAR
Kafkas Üniversitesi, Türkiye
Zihni Cagin
Kafkas Üniversitesi, Turkey
Zulfiye Kuzu
Kayseri City Hospital, Turkey
Prof. Dr. Yavuz KARABAĞ Prof. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Devamını Göster
Özet
Hypertension is a common and persistent disorder and mostly causes myocardial structural and functional abnormalities. As a subtype pattern of HT, the reverse-dipper blood pressure (BP) is associated with worse cardiovascular outcomes and early-phase subclinical myocardial damage compared to other patterns. The Left Atrial Coupling Index (LACI) is a novel echocardiographic parameter developed to assess the mechanical function. The aim of this study was to investigate the role of the LACI in predicting the reverse-dipper BP pattern in patients with hypertension. A total of 404 hypertensive patients who underwent 24-hour ambulatory blood pressure monitoring were prospectively enrolled. Patients were classified into dipper, non-dipper, and reverse-dipper groups based on their nocturnal BP profiles. Comprehensive echocardiographic evaluations were performed, and LACI was calculated for each patient. A reverse-dipper BP pattern was observed in 26%(n = 105) of the 404 patients. Those with a reverse-dipper BP pattern exhibited higher mitral E/A ratio, E/Em means, left atrial volume index (LAVI), and LACI, along with lower Em septal, Am lateral mitral, and Am septal values. LACI (OR:3.837, 95% CI: 2.620-5.620, p < 0.001), LAVI, and Am lateral mitral value were found to be independent predictors of the reverse-dipper BP pattern. ROC curve comparison demonstrated that LACI was a better predictor of the reverse-dipper BP pattern than LAVI. Our study demonstrates that LACI, an easily accessible echocardiographic parameter, is a more robust predictor of the reverse-dipper BP pattern compared to traditional echocardiographic markers.
Anahtar Kelimeler
Left Atrial Coupling Index | Reverse-dipper Blood Pressure Pattern | 24-hour Ambulatory Blood Pressure Monitoring | Hypertension | Nocturnal Blood Pressure Patterns
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION
Dergi ISSN 1120-9879 Wos Dergi Scopus Dergi
Makale Dili İngilizce
Basım Tarihi 07-2025
Sayı 1
Doi Numarası 10.1007/s40292-025-00733-w