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Nanoparticles: Synthesis and Their Role as Potential Drug Candidates for the Treatment of Parasitic Diseases     
Yazarlar (12)
Hammad Ur Rehman Bajwa
Ankara Üniversitesi, Turkey
Muhammad Kasib Khan
University of Agriculture, Faisalabad, Pakistan
Zaheer Abbas
University of Agriculture, Faisalabad, Pakistan
Dr. Öğr. Üyesi Roshan RIAZ Dr. Öğr. Üyesi Roshan RIAZ
Kafkas Üniversitesi, Türkiye
Tauseef Ur Rehman
The Islamia University of Bahawalpur, Pakistan
Rao Zahid Abbas
University of Agriculture, Faisalabad, Pakistan
Muhammad Tahir Aleem
Nanjing Agricultural University, China
Asghar Abbas
MNS-University of Agriculture, Multan, Pakistan
Mashal M. Almutairi
College of Pharmacy, Saudi Arabia
Fahdah Ayed Alshammari
Northern Border University, Saudi Arabia
Yasser Alraey
King Khalid University, Saudi Arabia
Abdulaziz Alouffi
King Abdulaziz City for Science and Technology, Saudi Arabia
Devamını Göster
Özet
Protozoa, helminths and ectoparasites are the major groups of parasites distributed worldwide. Currently, these parasites are treated with chemotherapeutic antiprotozoal drugs, anti-helminthic and anti-ectoparasitic agents, but, with the passage of time, resistance to these drugs has developed due to overuse. In this scenario, nanoparticles are proving to be a major breakthrough in the treatment and control of parasitic diseases. In the last decade, there has been enormous development in the field of nanomedicine for parasitic control. Gold and silver nanoparticles have shown promising results in the treatments of various types of parasitic infections. These nanoparticles are synthesized through the use of various conventional and molecular technologies and have shown great efficacy. They work in different ways, that include damaging the parasite membrane, DNA (Deoxyribonucleic acid) disruption, protein synthesis inhibition and free-radical formation. These agents are effective against intracellular parasites as well. Other nanoparticles, such as iron, nickel, zinc and platinum, have also shown good results in the treatment and control of parasitic infections. It is hoped that this research subject will become the future of modern drug development. This review summarizes the methods that are used to synthesize nanoparticles and their possible mechanisms of action against parasites.
Anahtar Kelimeler
mechanisms of action | nanoparticles | parasite control | synthesis
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCOPUS dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Life
Dergi ISSN 2075-1729 Wos Dergi Scopus Dergi
Makale Dili İngilizce
Basım Tarihi 05-2022
Cilt No 12
Sayı 5
Doi Numarası 10.3390/life12050750