Yazarlar (12) |
![]() Ankara Üniversitesi, Turkey |
![]() University of Agriculture, Faisalabad, Pakistan |
![]() University of Agriculture, Faisalabad, Pakistan |
![]() Kafkas Üniversitesi, Türkiye |
![]() The Islamia University of Bahawalpur, Pakistan |
![]() University of Agriculture, Faisalabad, Pakistan |
![]() Nanjing Agricultural University, China |
![]() MNS-University of Agriculture, Multan, Pakistan |
![]() College of Pharmacy, Saudi Arabia |
![]() Northern Border University, Saudi Arabia |
![]() King Khalid University, Saudi Arabia |
![]() King Abdulaziz City for Science and Technology, Saudi Arabia |
Özet |
Protozoa, helminths and ectoparasites are the major groups of parasites distributed worldwide. Currently, these parasites are treated with chemotherapeutic antiprotozoal drugs, anti-helminthic and anti-ectoparasitic agents, but, with the passage of time, resistance to these drugs has developed due to overuse. In this scenario, nanoparticles are proving to be a major breakthrough in the treatment and control of parasitic diseases. In the last decade, there has been enormous development in the field of nanomedicine for parasitic control. Gold and silver nanoparticles have shown promising results in the treatments of various types of parasitic infections. These nanoparticles are synthesized through the use of various conventional and molecular technologies and have shown great efficacy. They work in different ways, that include damaging the parasite membrane, DNA (Deoxyribonucleic acid) disruption, protein synthesis inhibition and free-radical formation. These agents are effective against intracellular parasites as well. Other nanoparticles, such as iron, nickel, zinc and platinum, have also shown good results in the treatment and control of parasitic infections. It is hoped that this research subject will become the future of modern drug development. This review summarizes the methods that are used to synthesize nanoparticles and their possible mechanisms of action against parasites. |
Anahtar Kelimeler |
mechanisms of action | nanoparticles | parasite control | synthesis |
Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
Makale Alt Türü | SCOPUS dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
Dergi Adı | Life |
Dergi ISSN | 2075-1729 Wos Dergi Scopus Dergi |
Makale Dili | İngilizce |
Basım Tarihi | 05-2022 |
Cilt No | 12 |
Sayı | 5 |
Doi Numarası | 10.3390/life12050750 |