| Yazarlar (6) |
S. Kızıltepe
Iğdır Üniversitesi, Türkiye |
|
C. Okulmus
Izmir/Bornova Veterinary Control Institute, Türkiye |
|
R. Akpınar
Bee Hospital Laboratory, Türkiye |
Prof. Dr. Oğuz MERHAN
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Kadir BOZUKLUHAN
Kafkas Üniversitesi, Türkiye |
|
Dr. Öğr. Üyesi Nüvit COŞKUN
Kafkas Üniversitesi, Türkiye |
| Özet |
| Understanding the zoonotic risk posed by the orf virus (ORFV), which causes contagious ecthyma in domestic animals, is crucial for both human and animal health. Contagious ecthyma is a highly contagious, zoonotic, viral skin disease that affects sheep, goats, and certain other domestic and wild animals. In this study, serum malondialdehyde (MDA), nitric oxide (NO), reduced glutathione (GSH) concentrations, and adenosine deaminase (ADA) activity were measured in healthy and naturally infected lambs with ecthyma. Compared to healthy lambs, serum MDA (respectively; 2.69±0.4 vs. 4.73±0.24 μmol/L, P<0.001), NO (respectively; 6.12±0.72 vs. 8.32±0.55μmol/L, P<0.05) and ADA (respectively; 7.12±0.60 vs. 21.53±1.82 U/L, P<0.001) concentrations increased, while GSH (respectively; 15.01±1.59vs. 10.05±1.10mg/dL, P<0.05) levels decreased in contagious ecthyma lambs. As a result, it was concluded that oxidative stress developed in lambs infected with contagious ecthyma, ADA enzyme activity increased, and this could be useful for the diagnosis of the disease. |
| Anahtar Kelimeler |
| Adenosine deaminase | ecthyma | lamb | oxidative stress |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Arquivo Brasileiro De Medicina Veterinaria E Zootecnia |
| Dergi ISSN | 0102-0935 Wos Dergi Scopus Dergi |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2025 |
| Cilt No | 77 |
| Sayı | 4 |
| Doi Numarası | 10.1590/1678-4162-13399 |
| Atıf Sayıları |
