| Yazarlar (11) |
Ayca Arslan
|
|
Dogan Ilis
|
|
Inanc Artac
|
Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye |
|
Timor Omar
Kafkas Üniversitesi, Türkiye |
|
Zihni Cagin
|
|
Zulfiye Kuzu
|
|
Ozcan Yagcibulut
|
|
Cengiz Burak
|
|
Yavuz Karabag
|
|
Ibrahim Rencuzogullari
|
| Özet |
| Hypertension (HT) is one of the most common causes of myocardial dysfunction. Although early detection of myocardial impairment remains challenging, left ventricular global longitudinal strain (LV-GLS) is a sensitive echocardiographic parameter that can identify subclinical myocardial damage. However, its application is limited in routine clinical settings. R-wave peak time (RWPT) is a simple and widely available electrocardiographic parameter that may reflect intramyocardial conduction delay and early structural remodeling. This study aimed to investigate the association between RWPT and LV-GLS in patients with HT. This prospective study included 403 patients with a confirmed diagnosis of HT. All participants underwent transthoracic echocardiography and 12-lead surface ECG. LV-GLS was assessed using speckle-tracking echocardiography. ECG images were digitized and analyzed using ImageJ software, and RWPT was defined as the interval from the onset of the QRS complex to the peak of the R-wave. Patients were divided into two groups according to their LV-GLS value of -15.9%, which is defined as the cutoff value of myocardial impairment. Patients with a lower LV-GLS had significantly longer RWPT and QRS durations. In multivariate analysis, RWPT was found to be an independent predictor of impaired LV-GLS (OR: 1.085; 95% CI: 1.056-1.114; P < 0.001). ROC analysis demonstrated an AUC of 0.715 (95% CI: 0.665-0.765; P < 0.001) with a sensitivity of 64.9% and a specificity of 67.7% at a cutoff value of 45.5 ms. RWPT may serve as a practical, accessible, and sensitive electrocardiographic marker for detecting subclinical myocardial dysfunction in patients with HT. |
| Anahtar Kelimeler |
| blood pressure | electrocardiography | hypertension | left ventricular global longitudinal strain | R-wave peak time | subclinical myocardial dysfunction |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
| Dergi Adı | AMERICAN JOURNAL OF HYPERTENSION |
| Dergi ISSN | 0895-7061 Wos Dergi Scopus Dergi |
| Makale Dili | İngilizce |
| Basım Tarihi | 09-2025 |
| Doi Numarası | 10.1093/ajh/hpaf180 |
| Atıf Sayıları |
