| Yazarlar (4) |
Dr. Öğr. Üyesi Nurullah ÇİFTÇİ
Kafkas Üniversitesi, Türkiye |
Salih Maçin
Selçuk Üniversitesi, Türkiye |
|
Gülcan Saylam Kurtipek
Türkiye |
|
Uğur Arslan
Selçuk Üniversitesi, Türkiye |
| Özet |
| Urticaria is a skin disorder characterized by erythematous, edematous, and pruritic lesions. Intestinal microorganisms can trigger various immunological responses, and Blastocystis has been suggested to affect gut-associated lymphoid tissue homeostasis and induce allergic reactions. This study aimed to evaluate the effect of Blastocystis on the intestinal microbiota in patients with urticaria. A total of 33 patients diagnosed with urticaria and 34 healthy controls were included. Independent sample t-tests, Welch’s t-tests, or Mann–Whitney U tests were applied to assess differences in the Shannon, Simpson, and Chao-1 indices between groups. Significant differences were observed in Proteobacteria (p = 0.015), Bacteroidetes (p = 0.008), Escherichia (p = 0.005), Phocaelcola (p = 0.043), and Prevotella (p = 0.047) between the urticaria and control groups. Bacteroidetes (p = 0.003) and Phocaelcola (p = 0.032) also differed significantly between samples with and without Blastocystis. Overall microbiota composition showed a significant difference between Blastocystis-positive and -negative samples (p = 0.009). The Firmicutes/Bacteroidetes ratio was 4.1 in healthy controls and 6.4 in urticaria patients. In conclusion, both urticaria and Blastocystis infection significantly influence intestinal microbiota composition, suggesting a potential interaction between Blastocystis colonization and host immune regulation in urticaria. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Pathogens |
| Dergi ISSN | 2076-0817 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | Türkçe |
| Basım Tarihi | 11-2025 |
| Cilt No | 14 |
| Sayı | 11 |
| Sayfalar | 1140 / 0 |
| Doi Numarası | 10.3390/pathogens14111140 |
| Makale Linki | https://doi.org/10.3390/pathogens14111140 |
| Atıf Sayıları |
