Synthesis and Characterization of α-(acetylhydrazono)-benzylacetic Acid and Its Complexes with Trace Elements: Molecular Docking and Antimicrobial Activities
Yazarlar (6)
Gulu Abbasova
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Ajdar Medjidov
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Rayyat İsmayilova
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Doç. Dr. Mustafa SERTÇELİK Kafkas Üniversitesi, Türkiye
Mansura Huseynova
Academician A.M. Guliyev Institute Of Chemistry Of Additives Ministry Of Science And Education Repub, Azerbaycan
Academician A.M. Guliyev Institute Of Chemistry Of Additives Ministry Of Science And Education Repub, Azerbaycan
Mahammad Bayramov
Institute Of Radiation Problems Ministry Of Science And Education Republic Of Azerbaijan, Azerbaycan
Institute Of Radiation Problems Ministry Of Science And Education Republic Of Azerbaijan, Azerbaycan
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Letters in Organic Chemistry (Q3) | ||
| Dergi ISSN | 1570-1786 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2026 |
| Cilt / Sayı / Sayfa | 23 / 5 / 329–337 | DOI | 10.2174/0115701786413126251023111710 |
| Makale Linki | https://doi.org/10.2174/0115701786413126251023111710 | ||
| UAK Araştırma Alanları |
Anorganik Kimya
Spektroskopi
Teorik Kimya
|
||
| Özet |
| A new ligand containing a hydrazone group based on acetylhydrazine and phenylglyoxylic acid – α-(acetylhydrazono)-benzylacetic acid (1) and its copper (2a), zinc (2b), and manganese (2c) complexes were synthesized. The structures of the obtained compounds were investigated by IR, UV, NMR, and EPR spectroscopy. The molar ratio of the ligand and metal in the complex 2:1 was confirmed by elemental and thermogravimetric analysis. An octahedral geometry is proposed for all investigated metal complexes. Despite extensive studies on hydrazone-based Schiff bases, few have integrated synthesis, spectroscopic characterization, antimicrobial evaluation, and molecular docking to develop new agents with enhanced biocidal activity. This study addresses this gap. Antimicrobial activity tests showed that compounds 1, 2a, and 2b exhibited inhibition zones ranging from 2.5 to 3.0 cm against tested bacteria and … |
| Anahtar Kelimeler |
| antimicrobial activities | Hydrazones | molecular docking | phenylglyoxylic acid | Schiff base | trace elements |