The Effect of Caffeine on Wnt/β‐Catenine and P38 Mitogen‐Activated Protein Kinases (MAPK) Signal Pathways and Some Biochemical Parameters on Cafeteria Diet in Rats
Yazarlar (2)
Dr. Öğr. Üyesi Lale BAŞER Kafkas Üniversitesi, Türkiye
Prof. Dr. Emine ATAKİŞİ Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Food Science & Nutrition (Q2) | ||
| Dergi ISSN | 2048-7177 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 11-2025 |
| Cilt / Sayı / Sayfa | 13 / 11 / – | DOI | 10.1002/fsn3.71138 |
| Makale Linki | https://doi.org/10.1002/fsn3.71138 | ||
| UAK Araştırma Alanları |
Veteriner Biyokimyası
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| Özet |
| Obesity is a major noncommunicable public health problem that is rapidly spreading worldwide, arising from an imbalance between energy intake and expenditure, and various interventions have been attempted for its treatment. This study evaluated the impact of caffeine on metabolic and hepatic parameters in rats with obesity induced by a cafeteria diet. Rats were assigned to control, caffeine, obesity, and obesity + caffeine groups. The cafeteria diet effectively promoted obesity, as evidenced by increased body weight, BMI, and Lee Index, accompanied by elevated serum glucose, triglycerides, total cholesterol, low‐density lipoprotein (LDL), very low‐density lipoprotein (VLDL), and reduced high‐density lipoprotein (HDL) levels. Obesity also led to higher plasma asprosin and visfatin levels, decreased hepatic β‐catenin and P38 mitogen‐activated protein kinases (p38 MAPK) expression, and histopathological … |
| Anahtar Kelimeler |
| MAPK | cafeteria diet | caffeine | obesity | signaling pathways | β‐catenin |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |
| PubMed | 1 |