Effects of hydrogen‐rich water on growth, redox homeostasis and hormonal, histological and immune systems in rats exposed to high cage density stress
Yazarlar (11)
Doç. Dr. Buket BOĞA KURU Kafkas Üniversitesi, Türkiye
Doç. Dr. Mustafa MAKAV Kafkas Üniversitesi, Türkiye
Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye
Doç. Dr. Şükran YEDİEL ARAS Kafkas Üniversitesi, Türkiye
Prof. Dr. Ebru KARADAĞ SARI Kafkas Üniversitesi, Türkiye
Doç. Dr. Menekşe Bulut Iğdır Üniversitesi, Türkiye
Prof. Dr. Dureyt Veziroğlu Iğdır Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fikret BEKTAŞOĞLU Kafkas Üniversitesi, Türkiye
Doç. Dr. Mükremin ÖLMEZ Kafkas Üniversitesi, Türkiye
Prof. Dr. Turgut KIRMIZIBAYRAK Kafkas Üniversitesi, Türkiye
Tyler W. Lebaron
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | VETERINARY MEDICINE AND SCIENCE (Q2) | ||
| Dergi ISSN | 2053-1095 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2025 |
| Cilt / Sayı / Sayfa | 11 / 2 / 70305– | DOI | 10.1002/vms3.70305 |
| Makale Linki | https://doi.org/10.1002/vms3.70305 | ||
| UAK Araştırma Alanları |
Veteriner Zootekni
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| Özet |
| This study investigated the impact of drinking hydrogen-rich water (HRW) on growth performance, organ weights, thiol/disulphide homeostasis, oxidative status and some hormonal, histopathological and immunohistochemical changes in rats fed in a restricted housing environment. The eight groups (each group [male/female] eight rats) comprised two control, two hydrogen, two stress and two stress + hydrogen. All animals were given feed and water ad libitum for 3 months. Control and HRW group rats were calculated according to weight and housed according to the Guide's housing condition. The stress group and stress + HRW group were housed in half the area of the Guide's housing condition according to their weight. The animal's weekly body weights were measured throughout the study. The animals were sacrificed in accordance with ethical rules. Then, biochemical analyses were performed on thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), cortisol, parathyroid hormone (PTH) and calcium (Ca), total thiol (TT), native thiol (NT), disulphide, disulphide/TT × 100, disulphide/NT × 100 and NT/TT × 100, malondialdehyde (MDA) and glutathione (GSH). Haematoxylin staining for histopathological and SOD-2 immunoreactivity was also assessed. Results showed that live weight gain was higher in the HRW groups than in the stress group. Oxidant status in biochemical analyses decreased in the stress + HRW group compared to the stress group. TSH decreased in the stress group. FT4, cortisol and Ca increased in the stress group. The stress-related physiological parameters were reduced in the HRW + stress group compared to the stress group. HRW could be suggested when the organism is found in stressful conditions. |
| Anahtar Kelimeler |
| growth performance | hydrogen-rich water | molecular hydrogen | oxidative status | stress |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 4 |