Relationship Between the Lactate-to-Albumin Ratio and Acute Kidney Injury in Patients with Pulmonary Embolism: A Retrospective Cohort Study
Yazarlar (10)
Doç. Dr. Doğan İLİŞ Kafkas Üniversitesi, Türkiye
Doç. Dr. Ayça ARSLAN Kafkas Üniversitesi, Türkiye
Doç. Dr. İnanç ARTAÇ Kafkas Üniversitesi, Türkiye
Doç. Dr. Muammer KARAKAYALI Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ömer Kertmen Amasya Üniversitesi, Türkiye
Hatice Taşkan
University Of Health Sciences, Türkiye
University Of Health Sciences, Türkiye
Yüksel Erata
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
Arş. Gör. Ezgi Güzel Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Medicina Lithuania (Q1) | ||
| Dergi ISSN | 1010-660X Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2026 |
| Cilt / Sayı / Sayfa | 62 / 3 / 1–12 | DOI | 10.3390/medicina62030474 |
| Makale Linki | https://doi.org/10.3390/medicina62030474 | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| Background and Objectives: Pulmonary embolism (PE), the third most prevalent cause of cardiovascular death, is often regarded as a potentially fatal condition. Renal function has been shown to affect the short- and long-term prognosis of acute PE in several large registries. Therefore, the purpose of this study is to investigate the relationship between acute kidney injury (AKI) and the lactate-to-albumin ratio (LAR) in patients hospitalized for PE. Materials and Methods: 264 PE patients were included in this retrospective analysis. Based on the presence or absence of AKI, the study population was split into two groups. Results: Of the 264 patients included in our study, 161 (61%) were female. The median age was 67 ± 16 years. The sample was divided into two groups based on whether AKI developed (No AKI group, n = 176; AKI group, n = 88). A multivariate logistic regression analysis revealed that sPESI score, receiving fibrinolytic therapy (tPA), and LAR (OR: 6.334, 95% CI: 3.070–13.069; p < 0.001) were independently associated with AKI in patients with PE. In particular, an LAR > 0.55 predicted AKI in patients with PE, with a sensitivity of 75% and a specificity of 67% (AUC = 0.749, 95% CI = 0.692–0.800, p < 0.001). Conclusions: Our study demonstrates that the LAR independently predicts AKI in patients with PE. This is the first study that precisely examines this association in PE patients, as far as we are aware. |
| Anahtar Kelimeler |
| pulmonary embolism; lactate-to-albumin ratio; acute kidney injury |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 1 |
| Google Scholar | 1 |