Validated electrochemical immunosensor for ultra-sensitive procalcitonin detection: carbon electrode modified with gold nanoparticles functionalized sulfur doped MXene as …
Yazarlar (1)
Doç. Dr. Murat BEYTUR Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Sensors and Actuators B: Chemical | ||
| Makale Dili | – | Basım Tarihi | 09-2020 |
| Cilt / Sayı / Sayfa | 319 / 0 / 128195–0 | DOI | – |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S0925400520305402 | ||
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| Septicemia, also known as sepsis, refers to a systemic inflammatory response syndrome and becomes the dominant reason of mortality for seriously diseases. Procalcitonin (PCT), the peptide precursor of the hormones, is a key biomarker of septicemia in the diagnosis and detection of bacterial inflammation. In this study, an ultra-sensitive sandwich type electrochemical immunosensor for PCT detection was constructed. Firstly, delaminated sulfur-doped MXene (d-S-Ti3C2TX MXene) modified glassy carbon electrode (GCE) including gold nanoparticles (AuNPs) was utilized as immunosensor platform to increase the amount of PCT antibody1 (Ab1). After that, carboxylated graphitic carbon nitride (c-g-C3N4) was used to label PCT Ab2 as signal amplification. The structure of electrochemical immunosensor was highlighted by x-ray diffraction (XRD) method, scanning electron microscope (SEM), transmission electron … |
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