Evaluation of 4-Hydroxy-2-Nonenal, Dityrosine and 8-Hydroxy-2-Deoxyguanosine Expressions in Lambs with White Muscle Disease
Yazarlar (7)
Doç. Dr. Emin KARAKURT Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Özhan Karataş Sivas Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Serpil DAĞ Kafkas Üniversitesi, Türkiye
Prof. Dr. Enver BEYTUT Kafkas Üniversitesi, Türkiye
Ali Sefa Mendil
Erciyes Üniversitesi, Türkiye
Erciyes Üniversitesi, Türkiye
Dr. Öğr. Üyesi Hilmi NUHOĞLU Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ayfer YILDIZ UYSAL Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
|
||
| Dergi Adı | Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi | ||
| Dergi ISSN | 1308-9323 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2021 |
| Cilt / Sayı / Sayfa | 35 / 2 / 109–113 | DOI | – |
| Makale Linki | http://veteriner.fusabil.org/pdf/pdf_FUSABIL_1524.pdf | ||
| UAK Araştırma Alanları |
Veterinerlik Patolojisi
|
||
| Özet |
| The aim of this study was to investigate Reactive Oxygen Species (ROS)-induced lipid peroxidation, protein and DNA damage with oxidative stress markers such as 4-hydroxy-2-nonenal (4-HNE), dityrosine (DT) and 8-hydroxy-2-deoxyguanosine (8-OHdG) in lambs with White Muscle Disease (WMD). The material of this study consisted of tissue samples taken from 20 sheep with WMD and 6 healthy control groups brought to Pathology Department for routine histopathological diagnosis between 2012 and 2019. In macroscopic examinations, chalky-white large necrotic areas on the epicardial and especially on the endocardial surfaces of the right and left ventricular walls were observed. In microscopic examinations, it was observed that the degenerated muscle fibers in the heart were homogeneously pink in color, lost their cytoplasmic citration, swelled and their nuclei were pyknotic. Calcifications in necrotic and … |
| Anahtar Kelimeler |
