Investigation of surfactant apoproteins and Brucella sp. antigens in the lungs of aborted bovine fetuses and neonatal calves delivered weak
 
Yazarlar (4)
Prof. Dr. Enver BEYTUT Kafkas Üniversitesi, Türkiye
Prof. Dr. Mahmut Sözmen Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. Emin KARAKURT Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Hilmi NUHOĞLU Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Research in Veterinary Science (Q2)
Dergi ISSN 0034-5288 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 12-2024
Cilt / Sayı / Sayfa 181 / 1 / – DOI 10.1016/j.rvsc.2024.105445
Makale Linki https://www.sciencedirect.com/science/article/pii/S0034528824003126
UAK Araştırma Alanları
Veteriner Patolojisi
Özet
The main objectives of this study were to investigate surfactant apoprotein expression (SP) and to detect Brucella sp. antigens in the lungs of aborted bovine fetuses and neonatal calves delivered weak. The Avidin-Biotin-Peroxidase Complex (ABC) and the indirect immunofluorescence (IF) techniques were applied, using antibodies to the lung surfactant apoproteins (SP-A, SP-B, SP-C) and Brucella sp. antigens. Hyperplasia of type II cells was also assessed by evaluating Thyroid Transcription Factor-1 (TTF-1), Proliferating Cell Nuclear Antigen (PCNA), and Cytokeratin Pan Type I/II (CK-P) markers. The study materials were the lungs of 46 aborted bovine fetuses and 20 neonatal calves delivered weak. Brucella sp.-positive fetal lungs displayed bronchopneumonia in 24 cases. The lungs of the weak-delivered neonates which were positive for Brucella sp. also showed pneumonia. Bacterial culture detected positivity …
Anahtar Kelimeler
Bovine | Brucella | Fetus | Lung | Neonates | Surfactant