Boric acid and Borax Supplementation Reduces Weight Gain in Overweight Rats and Alter L-Carnitine and IGF-I Levels
  
Yazarlar (7)
Prof. Dr. Onur ATAKİŞİ Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Kezban YILDIZ DALGINLI Kafkas Üniversitesi, Türkiye
Rüya Kaya Ağrı İbrahim Çeçen Üniversitesi, Türkiye
Prof. Dr. Özkan ÖZDEN Kafkas Üniversitesi, Türkiye
Asım Kart Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
Prof. Dr. Emine ATAKİŞİ Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı International Journal for Vitamin and Nutrition Research
Dergi ISSN 0300-9831 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 02-2020
Cilt / Sayı / Sayfa – / 0 / 1–7 DOI 10.1024/0300-9831/a000518
Makale Linki https://econtent.hogrefe.com/doi/10.1024/0300-9831/a000518
Özet
The aim of this study was to investigate the effects of boric acid (BA) and borax (BX) on live weight and obesity associated molecules including leptin, L-carnitine, insulin-like growth factor 1 (IGF-I), and heat shock proteins 70 (HSP70) in rats fed with high-fat diet. A total of 60 rats were equally allocated as ND (normal diet), HF (high-fat diet), HF+ BA, HF+ BX, ND+ BX, ND+ BA. Body weight increases in HF+ BA (85 g) and HF+ BX (86 g) were significantly lower (p< 0.05) compared to HF group (126 g). Boron treatment decreased serum L-carnitine level in high-fat diet (HF+ BA 11.12 mg/L, HF+ BX 10.51 mg/L, p< 0.05) compared to HF group (15.57 mg/L), while no change was observed in groups ND+ BA (7.55 mg/L) and ND+ BX (7.57 mg/L) compared to group ND (8.29 mg/L). Neither BA nor BX supplementation in ND and HF groups altered the serum levels of HSP70 and leptin. BA and BX supplementation in rats fed …
Anahtar Kelimeler