Immunohistochemical Detection of Pulmonary Surfactant Proteins and Retroviral Antigens in the Lungs of Sheep with Pulmonary Adenomatosis
Yazarlar (3)
Prof. Dr. Enver BEYTUT Kafkas Üniversitesi, Türkiye
M. Sözmen
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
S. Ergínsoy Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Comparative Pathology (Q1) | ||
| Dergi ISSN | 0021-9975 Dergi Bilgileri (2009) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2009 |
| Cilt / Sayı / Sayfa | 140 / 1 / 43–53 | DOI | 10.1016/j.jcpa.2008.10.003 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0021997508001400 | ||
| UAK Araştırma Alanları |
Veterinerlik Patolojisi
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| Özet |
| The lungs and mediastinal and bronchial lymph nodes from 26 sheep with ovine pulmonary adenomatosis (OPA) were examined. Microscopically, the tumour was disseminated throughout the lungs and displayed acinar or papillary growth. The neoplastic cells were cuboidal or columnar with clear cytoplasm and a low mitotic rate. Retrovirus antigen (Jaagsiekte Sheep Retrovirus Capsid Protein, JSRV CA) was demonstrated in the cytoplasm of tumour cells in the lung and lymph nodes by immunohistochemistry. The neoplastic cells had more diffuse and intense expression of pulmonary surfactant protein-A (SP-A) compared with the expression of SP-B or SP-C. SP-A and SP-B expression was localized to the apical cytoplasm of the neoplastic cells, whereas SP-C was most strongly expressed in the perinuclear area of the tumour cells. In the lungs of two sheep, low numbers of tumour cells expressed Clara cell … |
| Anahtar Kelimeler |
| lungs | ovine pulmonary adenomatosis | pulmonary surfactant protein | retrovirus |
Science Direct
Immunohistochemical Detection of Pulmonary Surfactant Proteins and Retroviral Antigens in the Lungs of Sheep with Pulmonary Adenomatosis
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 35 |
| Scopus | 39 |
| Google Scholar | 57 |