Immunohistochemical evaluation of surfactant proteins and lymphocyte phenotypes in the lungs of cattle with natural tuberculosis
Yazarlar (1)
Prof. Dr. Enver BEYTUT Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Research in Veterinary Science (Q1) | ||
| Dergi ISSN | 0034-5288 Dergi Bilgileri (2011) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2011 |
| Cilt / Sayı / Sayfa | 91 / 1 / 119–124 | DOI | 10.1016/j.rvsc.2010.07.023 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0034528810002596 | ||
| UAK Araştırma Alanları |
Veterinerlik Patolojisi
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| Özet |
| The aim of the present study was to evaluate the immunohistochemical expression of pulmonary surfactant proteins (SP-A, SP-B, SP-C) and lymphocytic phenotypes in the lungs of 12 cattle with natural tuberculosis. Grossly, the disease-affected cattle revealed numerous granulomas in the lung lobes. Histopathological examination found multiple lung granulomas with typical cellular elements. Type II pneumocytes with adenomatous proliferation around the granulomas were strongly immunopositive for SP-A and SP-B compared to normal type II cells. Clara cells showed also cytoplasmic immunopositivity for these surfactant proteins. Positive immunolabelling for proSP-C was detected exclusively in the normal and proliferative type II pneumocytes, and the reaction was marked in the perinuclear area of the cells. CD3+ T and CD79αcy+ B lymphocytes were predominantly localized in the fibrotic capsule margin of … |
| Anahtar Kelimeler |
| Cattle | Immunohistochemistry | Lungs | Lymphocytes | Surfactant proteins | Tuberculosis |
Science Direct
Immunohistochemical evaluation of surfactant proteins and lymphocyte phenotypes in the lungs of cattle with natural tuberculosis
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 7 |
| Scopus | 8 |
| Google Scholar | 11 |