Enantioselective Assembly of Tricyclic Tetrahydroquinoline Derivatives
Yazarlar (4)
Doç. Dr. Erbay KALAY Kafkas Üniversitesi, Türkiye
Doç. Dr. Elif Akın Kazancıoğlu Türkiye
Vsevolod A Peshkov
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | CHEMISTRYSELECT (Q3) | ||
| Dergi ISSN | 2365-6549 Dergi Bilgileri (2019) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2019 |
| Kabul Tarihi | 24-07-2019 | Yayınlanma Tarihi | 08-08-2019 |
| Cilt / Sayı / Sayfa | 4 / 30 / 8797–8799 | DOI | 10.1002/slct.201902249 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/abs/10.1002/slct.201902249 | ||
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| Abstract A three‐step synthetic route towards enantioenriched tricyclic tetrahydroquinoline derivatives has been investigated. The first step involved the assembly of 4‐amino‐tetrahydroquinoline core through the asymmetric three‐component Povarov reaction of benzyl ( E )‐prop‐1‐en‐1‐ylcarbamate and p ‐anisidine with aliphatic aldehydes of various length bearing protected hydroxyl group. The alcohol was then deprotected and employed in an intramolecular reaction with a secondary amine of tetrahydroquinoline moiety producing desired tricyclic scaffolds. |
| Anahtar Kelimeler |
| Asymmetric synthesis | Multicomponent reactions | Nitrogen heterocycles | Povarov reaction | Tetrahydroquinolines |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 14 |