| Yazarlar (9) |
Mustafa Can Güler
Atatürk Üniversitesi, Türkiye |
|
Ayhan Tanyeli
Atatürk Üniversitesi, Türkiye |
|
Ersen Eraslan
Yozgat Bozok Üniversitesi, Türkiye |
|
Mehmet Ramazan Bozhüyük
Türkiye |
|
Fazile Nur Ekinci Akdemir
Ağrı İbrahim Çeçen Üniversitesi, Türkiye |
Doç. Dr. Erdem TOKTAY
Kafkas Üniversitesi, Türkiye |
|
Nezahat Kurt
Erzincan Binali Yıldırım Üniversitesi, Türkiye |
|
Esra Çapanoğlu Güven
Türkiye |
|
Gülay Özkan
İstanbul Teknik Üniversitesi, Türkiye |
| Özet |
| Objective: The worldwide incidence of a gastric ulcer is high, most often as a result of useof nonsteroidal anti-inflammatory drugs, excessive alcohol consumption, or Helicobacterpylori infection. An ethanol-based gastric ulcer model in rats was used to examine the effectof persimmon (Diospyros kaki L.) extract as a potential form of treatment.Methods: Two dosages of persimmon extract were applied in a gastric ulcer model createdwith 5 mL/kg ethanol in Wistar albino rats. Histopathological and biochemical methods wereused to assess any gastroprotective effects.Results: Persimmon extract significantly decreased the level of the cytokines interleukin(IL)-10, IL-6, tumor necrosis factor alpha (TNF-α) and IL-1 beta. Caspase-3 and nuclearfactor kappa B expression was also significantly reduced.Conclusion: Persimmon fruit extract demonstrated a gastroprotective effect in an ethanol-based gastric ulcer model in rats. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale |
| Dergi Adı | Southern Clinics of Istanbul Eurasia |
| Dergi ISSN | 2587-0998 |
| Dergi Tarandığı Indeksler | TR DİZİN |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2021 |
| Cilt No | 1 |
| Sayı | 32 |
| Sayfalar | 1 / 7 |
| Doi Numarası | 10.14744/scie.2020.94546 |
| Makale Linki | http://dx.doi.org/10.14744/scie.2020.94546 |
| Atıf Sayıları | |
| TRDizin | 3 |
