| Yazarlar (5) |
Muhitdin Yılmaz
Sinop Üniversitesi, Türkiye |
|
Yusuf Ersan
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Evren KOÇ
Kafkas Üniversitesi, Türkiye |
|
Hasan Özen
Kafkas Üniversitesi, Türkiye |
|
Musa Karaman
Balıkesir Üniversitesi, Türkiye |
| Özet |
| Effects of high water cadmium sulphate hydrate (3CdSO4 * 8H2O) (CdSO4) levels on the expression of serum proteins and tissue histopathology of the European chub (Leuciscus cephalus) was investigated. Three groups of fish (control, 1st, and 2nd), each containing 10 animals, were placed in separate tanks containing no, 1 mg/L, and 2 mg/L CdSO4, respectively, for 10 days. At the end of the study period, blood samples were taken and sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) was performed. Fish tissue samples were taken then routinely processed and stained with hematoxylin and eosin to observe histopathological changes. Depending on the increasing concentration of CdSO4, a gradual decrease in protein bands was determined. Inhibition of 35.3 kilodalton (kD) and 100.5 kD proteins in the 1st group and of 44.5 kD and 47.3 kD proteins in the 2nd group was detected. Microscopic examination revealed degeneration in the secondary lamellar epithelia, hydropic degeneration and necrosis in chloride cells of the fish gill in CdSO4 given groups. Hydropic degeneration and necrosis were also observed in light to severe levels in the liver depending on the groups. It was concluded that CdSO4 has toxic effects on the expression of serum proteins and causes degenerative changes on gill and liver morphology in Leuciscus cephalus. |
| Anahtar Kelimeler |
| Cadmium sulphate | Serum protein | SDS-PAGE | Histopathology | Leuciscus cephalus |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI |
| Dergi ISSN | 1300-6045 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2011 |
| Cilt No | 17 |
