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Synthesis and Structural Characterization of Novel 2-Aminomethyl Quinazolin-4(3H)-ones as Organic Building Blocks    
Yazarlar
Doç. Dr. Feyzi Sinan TOKALI
Kafkas Üniversitesi, Türkiye
Özet
Quinazoline and quinazolinone derivatives display an extensive application in organic and pharmaceutical chemistry, and they have been used as natural and synthetic materials for medicinal chemistry purposes. Here I reported an investigation of a new series of quinazolinone ring derivatives. In this context, starting from the methyl anthranilate, six quinazolinone derivatives (4a-f) with various aminomethyl moieties at position 2 were synthesized (89-80%). The structures of compounds 4a-f were identified using FTIR and NMR Spectroscopy (1H NMR - 13C NMR). The data obtained from the all spectra clearly identify the structures of the compounds.
Anahtar Kelimeler
Quinazoline,quinazolinone,synthesis,building blocks,NMR
Makale Türü Özgün Makale
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale
Dergi Adı Sakarya University Journal of Science
Dergi ISSN 1301-4048
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce
Basım Tarihi 12-2022
Cilt No 26
Sayı 6
Sayfalar 1117 / 1130
Doi Numarası 10.16984/saufenbilder.1085086
Makale Linki http://dx.doi.org/10.16984/saufenbilder.1085086