Copper 4-chlorobenzoate with isonicotinamide: synthesis, crystal structure, optical characterization and anticancer and cytotoxic properties
Yazarlar (5)
Alpaslan İşkey
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
Doç. Dr. Füreya Elif ÖZTÜRKKAN Kafkas Üniversitesi, Türkiye
Doç. Dr. Giray Buğra AKBABA Kafkas Üniversitesi, Türkiye
Doç. Dr. Mustafa SERTÇELİK Kafkas Üniversitesi, Türkiye
Tuncer Hökelek
Hacettepe Üniversitesi, Türkiye
Hacettepe Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of the Iranian Chemical Society (Q3) | ||
| Dergi ISSN | 1735-207X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2023 |
| Cilt / Sayı / Sayfa | 20 / 1 / 97–107 | DOI | 10.1007/s13738-022-02656-y |
| Makale Linki | http://dx.doi.org/10.1007/s13738-022-02656-y | ||
| Özet |
| In this study, a new metal complex, bis(μ-4-chlorobenzoato-κ2O:O′)bis[(4-chlorobenzoato-κ2O:O′-bis(isonicotinamide-κN)copper(II)] (1), was synthesized. The crystal structures of the complex were determined by single-crystal XRD. In addition, the structure was characterized by elemental analysis and FTIR spectroscopy. The intermolecular interactions of the complex were determined by Hirshfeld surface analysis. The optical and fluorescence properties of the complex were recorded with the help of UV–Vis and fluorescence spectrophotometer. In addition, the anticarcinogenic effects of the complex on DLD-1, MCF-7 and PC-3 cell lines and their cytotoxic properties on human lymphocyte cells were investigated by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. The complex has a dimeric structure. The intermolecular interactions that contribute the most to the crystal structure are H … |
| Anahtar Kelimeler |
| 4-Chlorobenzoic acid | Anticancer | Copper complex | Fluorescence | Molecular docking | MTT assay |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |