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Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells   
Yazarlar
Doç. Dr. Giray Buğra AKBABA Doç. Dr. Giray Buğra AKBABA
Kafkas Üniversitesi, Türkiye
Özet
Cerium(IV) oxide (CeO2) is widely used in industrial fields such as biomedical, glass, electronics,automotive, and pharmacology. In this study, the cytotoxic effects on human peripheral blood cultures oftwo forms of cerium(IV) oxide with different particle sizes (Bulk-sized Cerium(IV) oxide: BC and Nanosized Cerium(IV) oxide: NC) in concentrations range of 0.001-200 ppm were investigated. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay were used to determine thecytotoxicity of these forms. According to the test results, it was determined that both forms caused severecytotoxicity at all concentrations studied. It was observed that cytotoxicity increased with increasingconcentration. NCs are more toxic at all concentrations except 100 and 200 ppm concentrations.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale
Dergi Adı Journal of the Turkish Chemical Society Section A: Chemistry
Dergi ISSN 2149-0120
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce
Basım Tarihi 10-2021
Cilt No 8
Sayı 4
Sayfalar 1145 / 1152
Doi Numarası 10.18596/jotcsa.974814
Makale Linki http://dx.doi.org/10.18596/jotcsa.974814
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells

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