Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells
Yazarlar (1)
Doç. Dr. Giray Buğra AKBABA
Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
|
||
| Dergi Adı | Journal of the Turkish Chemical Society, Section A: Chemistry | ||
| Dergi ISSN | 2149-0120 Scopus Dergi | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2021 |
| Cilt / Sayı / Sayfa | 8 / 4 / 1145–1152 | DOI | 10.18596/jotcsa.974814 |
| Makale Linki | http://dx.doi.org/10.18596/jotcsa.974814 | ||
| Özet |
| Cerium(IV) oxide (CeO2) is widely used in industrial fields such as biomedical, glass, electronics,automotive, and pharmacology. In this study, the cytotoxic effects on human peripheral blood cultures oftwo forms of cerium(IV) oxide with different particle sizes (Bulk-sized Cerium(IV) oxide: BC and Nanosized Cerium(IV) oxide: NC) in concentrations range of 0.001-200 ppm were investigated. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay were used to determine thecytotoxicity of these forms. According to the test results, it was determined that both forms caused severecytotoxicity at all concentrations studied. It was observed that cytotoxicity increased with increasingconcentration. NCs are more toxic at all concentrations except 100 and 200 ppm concentrations. |
| Anahtar Kelimeler |
| Cerium (IV) oxide | MTT assay | nanoparticle | cytotoxicity | biomaterial | lymphocyte |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |