| Yazarlar |
Doç. Dr. Giray Buğra AKBABA
Kafkas Üniversitesi, Türkiye |
| Özet |
| Because zinc sulfate (ZnSO) is widely used in many fields such as biomedicine, electronics, and chemistry, it is important to evaluate its toxic effects. In this study, the cyto-genotoxic effects of ZnSO on meristematic cells in the root tip of L. were investigated. After calculating the effective concentration (EC = 70 ppm) of ZnSO, root tip cells were suspended for 24, 48, 72, and 96 h in solutions of 35 ppm (EC/2), 70 ppm (EC), and 140 ppm (EC × 2) concentrations. Using the counts of dividing cells, the mitotic index (MI) was calculated. Chromosome aberration index (CAI) was determined from percentages of abnormal cells. When the obtained data were statistically evaluated, it was determined that all application concentrations caused a significant decrease in MI and an increase in CAI compared to the control group (distilled water). It was concluded that increased ZnSO dose concentrations and exposure times caused cytotoxicity and genotoxicity in the root cells of L. |
| Anahtar Kelimeler |
| Allium cepaL,zinc sulfate,cytotoxicity,genotoxicity,risk assessment |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | TOXICOLOGY AND INDUSTRIAL HEALTH |
| Dergi ISSN | 0748-2337 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 10-2020 |
| Cilt No | 36 |
| Sayı | 10 |
| Sayfalar | 779 / 787 |
| Makale Linki | http://journals.sagepub.com/doi/10.1177/0748233720944771 |
