| Yazarlar |
Doç. Dr. Mustafa SERTÇELİK
Türkiye |
Doç. Dr. Füreya Elif ÖZTÜRKKAN
Türkiye |
Parham Taslımı
Türkiye |
Prof. Dr. Hacali NECEFOĞLU
Kafkas Üniversitesi, Türkiye |
|
Tuncer Hökelek
Türkiye |
| Özet |
| Two new complexes, [M (AB)2(CP)2(H2O)2] (where M = Ni and Co AB = 4-aminobenzoate and CP = cyanopyridine), were synthesized and characterized using different techniques (elemental analysis, FT-IR spectrophotometer, LC/MS, single-crystal X-ray diffraction, and TGA/DTA analysis). As a result of X-ray structural analysis, it was determined that complexes are isostructural. In the crystalline structures, MII ions are bridged with their carboxylate oxygen and aminopyridine nitrogen atoms and their symmetry-related counterparts to form a two-dimensional polymeric structure. The MII ion is octa-coordinated with two nitrogen atoms and two oxygen atoms of the AB and two atoms of the CP anions. In this study, the effect of these molecules, containing a biologically active group, was investigated on important metabolic enzymes (carbonic anhydrase isoenzymes I and II (hCA I and II), achethylcholinesterase (AChE), and α-glycosidase (α-Gly) enzymes). |
| Anahtar Kelimeler |
| 3-cyanopyridine | 4-aminobenzoate | metabolic enzyme inhibition | Ni and co complex | XRD |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | APPLIED ORGANOMETALLIC CHEMISTRY |
| Dergi ISSN | 0268-2605 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2021 |
| Cilt No | 35 |
| Sayı | 5 |
| Doi Numarası | 10.1002/aoc.6182 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/epdf/10.1002/aoc.6182 |
| Atıf Sayıları | |
| WoS | 8 |
| SCOPUS | 7 |
| Google Scholar | 9 |
