Supramolecular complexes of Ni (II) and Co (II) 4-aminobenzoate with 3-cyanopyridine: Synthesis, spectroscopic characterization, crystal structure, and enzyme inhibitory properties
Yazarlar (5)
Doç. Dr. Mustafa SERTÇELİK
Kafkas Üniversitesi, Türkiye
Doç. Dr. Füreya Elif ÖZTÜRKKAN
Kafkas Üniversitesi, Türkiye
Parham Taslımı
Bartin Üniversitesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU
Kafkas Üniversitesi, Türkiye
Tuncer Hökelek
Hacettepe Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Applied Organometallic Chemistry (Q1) | ||
| Dergi ISSN | 0268-2605 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2021 |
| Cilt / Sayı / Sayfa | 35 / 5 / – | DOI | 10.1002/aoc.6182 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/epdf/10.1002/aoc.6182 | ||
| Özet |
| Two new complexes, [M (AB)2(CP)2(H2O)2] (where M = Ni and Co AB = 4-aminobenzoate and CP = cyanopyridine), were synthesized and characterized using different techniques (elemental analysis, FT-IR spectrophotometer, LC/MS, single-crystal X-ray diffraction, and TGA/DTA analysis). As a result of X-ray structural analysis, it was determined that complexes are isostructural. In the crystalline structures, MII ions are bridged with their carboxylate oxygen and aminopyridine nitrogen atoms and their symmetry-related counterparts to form a two-dimensional polymeric structure. The MII ion is octa-coordinated with two nitrogen atoms and two oxygen atoms of the AB and two atoms of the CP anions. In this study, the effect of these molecules, containing a biologically active group, was investigated on important metabolic enzymes (carbonic anhydrase isoenzymes I and II (hCA I and II), achethylcholinesterase (AChE), and α-glycosidase (α-Gly) enzymes). |
| Anahtar Kelimeler |
| 3-cyanopyridine | 4-aminobenzoate | metabolic enzyme inhibition | Ni and co complex | XRD |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 10 |
| SCOPUS | 9 |
| Google Scholar | 11 |