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DNA binding study of tetraaqua bis p nitrobenzoato cobalt II dihydrate complex Co H 2 O 4 p NO 2 C 6 H 4 COO 2 center dot 2H 2 O       
Yazarlar
Ali Arslantaş
Karabük Üniversitesi, Türkiye
Alparslan Kadir Devrim
Kırıkkale Üniversitesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU Prof. Dr. Hacali NECEFOĞLU
Kafkas Üniversitesi, Türkiye
Özet
The interaction of [Co(H 2O) 4(p-NO 2C 6H 4COO) 2]. 2H 2O with sheep genomic DNA has been investigated by spectroscopic studies and electrophoresis measurements. The interaction between cobalt(II) p-nitrobenzoate and DNA has been followed by gel electrophoresis while the concentration of the complex was increased from 0 to 14 mM. The spectroscopic study and electrophoretic experiments support the fact that the complex binds to DNA by intercalation via p-nitrobenzoate into the base pairs of DNA. The mobility of the bands decreased as the concentration of complex was increased, indicating that there was increase in interaction between the metal ion and DNA. © 2007 by MDPI.
Anahtar Kelimeler
cobalt(II) complexes | DNA-binding | p-nitrobenzoate
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Dergi ISSN 1422-0067
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 07-2007
Cilt No 8
Sayı 7
Sayfalar 564 / 571
Doi Numarası 10.3390/i8070564