DNA binding study of tetraaqua bis p nitrobenzoato cobalt II dihydrate complex Co H 2 O 4 p NO 2 C 6 H 4 COO 2 center dot 2H 2 O
Yazarlar (3)
Ali Arslantas Kafkas Üniversitesi, Türkiye
A. Kadir Devrim
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | International Journal of Molecular Sciences | ||
| Dergi ISSN | 1422-0067 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2007 |
| Cilt / Sayı / Sayfa | 8 / 7 / 564–571 | DOI | 10.3390/i8070564 |
| Makale Linki | https://www.mdpi.com/1422-0067/8/7/564/pdf?version=1403129158 | ||
| Özet |
| The interaction of [Co(H2O)4(p-NO2C6H4COO)2]· 2H2O with sheep genomic DNA has been investigated by spectroscopic studies and electrophoresis measurements. The interaction between cobalt(II) p-nitrobenzoate and DNA has been followed by gel electrophoresis while the concentration of the complex was increased from 0 to 14 mM. The spectroscopic study and electrophoretic experiments support the fact that the complex binds to DNA by intercalation via p-nitrobenzoate into the base pairs of DNA. The mobility of the bands decreased as the concentration of complex was increased, indicating that there was increase in interaction between the metal ion and DNA. |
| Anahtar Kelimeler |
| Cobalt(II) complexes | DNA-binding | P-nitrobenzoate |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 16 |
| Web of Science | 12 |