Interactoon of genomic DNA with manganase II p aminobenzoate complex
Yazarlar (4)
Ali Arslantas Kafkas Üniversitesi, Türkiye
A. Kadir Devrim
Mehmet Akif University, Türkiye
Mehmet Akif University, Türkiye
Prof. Dr. Mahmut Sözmen Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Rasayan Journal of Chemistry | ||
| Dergi ISSN | 0974-1496 Dergi Bilgileri (2010) | ||
| Dergi Tarandığı Indeksler | Scopus | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2010 |
| Cilt / Sayı / Sayfa | 3 / 2 / 201–206 | DOI | – |
| UAK Araştırma Alanları |
Anorganik Kimya
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| Özet |
| The complex of bis-(p-aminobnzoato) tetraquamanganese (II) was synthesized according to the literature method. The interaction between bis-(p-aminobnzoato) tetraquamanganese (II) and cat genomic DNA was studied by gel electrophoresis, fluorescence spectroscopy, UV-visible and viscosity methods. The results suggest that the complex binds with DNA by intercalating through the ligand. The intrinsic binding constant Kb of [Mn (p-H2N-C6H4COO) 2]. 4H2O (MnPAB) was determined as 2.9 x 105 M-1. The binding constant shows that the complex binds to DNA. Also all the other experimental results proved that [Mn (p-H2N-C6H4COO) 2]. 4H2O could attach to DNA mainly by intercalative binding mode. |
| Anahtar Kelimeler |
| DNA binding | Gel electrophorsis | Interaction | Manganese(II) | P-aminobenzoic acid |