| Yazarlar |
Ali Arslantas
Kafkas Üniversitesi, Turkey |
|
A. Kadir Devrim
Mehmet Akif University, Turkey |
|
Mahmut Sözmen
Kafkas Üniversitesi, Veteriner Fakültesi, Turkey |
Hacali NECEFOĞLU
Kafkas Üniversitesi, Türkiye |
| Özet |
| The complex of bis-(p-aminobnzoato)tetraquamanganese(II) was synthesized according to the literature method. The interaction between bis-(p-aminobnzoato)tetraquamanganese(II) and cat genomic DNA was studied by gel electrophoresis, fluorescence spectroscopy, UV-visible and viscosity methods. The results suggest that the complex binds with DNA by intercalating through the ligand. The intrinsic binding constant Kb of [Mn(p-H2N-C6H4COO)2].4H2O (MnPAB) was determined as 2.9 x 105 M-1. The binding constant shows that the complex binds to DNA. Also all the other experimental results proved that [Mn(p-H2N-C6H4COO)2].4H2O could attach to DNA mainly by intercalative binding mode. |
| Anahtar Kelimeler |
| DNA binding | Gel electrophorsis | Interaction | Manganese(II) | P-aminobenzoic acid |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayımlanan tam makale |
| Dergi Adı | RASAYAN JOURNAL F CHEMISTRY |
| Dergi ISSN | 0974-1496 |
| Dergi Tarandığı Indeksler | Scopus |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2010 |
| Cilt No | 3 |
| Sayı | 2 |
| Sayfalar | 201 / 206 |
