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Investigation of DNA Binding Ability Between Di p aminobenzoato tetraaquacobalt II Complex and Cat Genomic DNA      
Yazarlar
Ali Arslantas
Kafkas Üniversitesi, Turkey
A. Kadir Devrim
Kafkas Üniversitesi, Turkey
Mahmut Sözmen
Kafkas Üniversitesi, Turkey
Prof. Dr. Hacali NECEFOĞLU Prof. Dr. Hacali NECEFOĞLU
Kafkas Üniversitesi, Türkiye
Özet
The di(p-aminobenzoato)tetraaquacobalt(II) complex [Co(PAB), where PAB is p-NH2C6H5CO2, has been obtained by the condensation of p-aminobenzoate in the presence of cobalt(II) sulfate. The interaction of complex of Co(PAB) with the cat genomic DNA was investigated by spectroscopic, gel electrophoresis, fluoresence spectroscopy and visco-sity measurements. The experimental data indicate that the complex may bind to DNA via an intercalative manner. The viscosity measurements and electrophoresis with spectroscopic studies support that complex, interacting with the cat genomic DNA by an intercalation mode through the base pairs of DNA. © 2009 by Mrs. Pushpa Agarwal, Managing Editor, Asian Journal of Chemistry, Sahibabad, India.
Anahtar Kelimeler
Co(II) complexes | DNA-binding | DNA | p-Amino benzoate
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı ASIAN JOURNAL OF CHEMISTRY
Dergi ISSN 0970-7077
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 10-2009
Cilt No 21
Sayı 8
Sayfalar 5888 / 5896
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları

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