Investigation of DNA Binding Ability Between Di p aminobenzoato tetraaquacobalt II Complex and Cat Genomic DNA
Yazarlar (4)
Ali Arslantas Kafkas Üniversitesi, Türkiye
A. Kadir Devrim
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
Prof. Dr. Mahmut Sozmen Kafkas Üniversitesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Asian Journal of Chemistry (Q4) | ||
| Dergi ISSN | 0970-7077 Dergi Bilgileri (2009) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2009 |
| Cilt / Sayı / Sayfa | 21 / 8 / 5888–5896 | DOI | – |
| UAK Araştırma Alanları |
Anorganik Kimya
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| Özet |
| The di(p-aminobenzoato)tetraaquacobalt(II) complex [Co(PAB), where PAB is p-NH2C6H5CO2, has been obtained by the condensation of p-aminobenzoate in the presence of cobalt(II) sulfate. The interaction of complex of Co(PAB) with the cat genomic DNA was investigated by spectroscopic, gel electrophoresis, fluoresence spectroscopy and viscosity measurements. The experimental data indicate that the complex may bind to DNA via an intercalative manner. The viscosity measurements and electrophoresis with spectroscopic studies support that complex, interacting with the cat genomic DNA by an intercalation mode through the base pairs of DNA. |
| Anahtar Kelimeler |
| Co(II) complexes | DNA | DNA-binding | P-Amino benzoate |
