| Yazarlar |
Ali Arslantas
Kafkas Üniversitesi, Turkey |
|
Mahmut Sozmen
Kafkas Üniversitesi, Veteriner Fakültesi, Turkey |
Prof. Dr. Hacali NECEFOĞLU
Kafkas Üniversitesi, Türkiye |
| Özet |
| Bis-(p-aminobenzoato)diaquanickel(II) [Ni(p-H2N-C6H4COO)2· 2H2O] and bis-(p-aminobenzoato)triaquacadmium(II) [Cd(p-H2NC6H4COO) 2·3H2O] complexes derived from p-aminobenzoate are reported. The genomic DNA interactions of these complexes with cat genomic DNA have been investigated with UV spectroscopy, gel electrophoresis and viscosity measurements. Ni(H2N-C6H4COO)2·2H2O and Cd(H2NC6H4COO)2·3H2O complexes exhibit interaction activities with DNA. The experimental results indicate that the complexes can bind to DNA via an intercalative mode. The intrinsic binding constants of the complexes with genomic DNA are 5.2 × 105-2.49 × 105 M-1, respectively. |
| Anahtar Kelimeler |
| Nickel (II) | Cadmium(II) | p-Aminobenzoic acid | DNA Binding | Gel electrophoresis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | ASIAN JOURNAL OF CHEMISTRY |
| Dergi ISSN | 0970-7077 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2010 |
| Cilt No | 22 |
| Sayı | 3 |
| Sayfalar | 1709 / 1716 |
