Interaction Studies of Bis p aminobenzoato diaquanickel II and Bis p aminobenzoato triaquacadmium II Complexes with Cat Genomic DNA
Yazarlar (3)
Ali Arslantas Kafkas Üniversitesi, Türkiye
Prof. Dr. Mahmut Sozmen Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Asian Journal of Chemistry (Q4) | ||
| Dergi ISSN | 0970-7077 Dergi Bilgileri (2010) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2010 |
| Cilt / Sayı / Sayfa | 22 / 3 / 1709–1716 | DOI | – |
| UAK Araştırma Alanları |
Anorganik Kimya
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| Özet |
| Bis-(p-aminobenzoato) diaquanickel (II)[Ni (p-H2N-C6H4COO) 2· 2H2O] and bis-(p-aminobenzoato) triaquacadmium (II)[Cd (p-H2NC6H4COO) 2· 3H2O] complexes derived from p-aminobenzoate are reported. The genomic DNA interactions of these complexes with cat genomic DNA have been investigated with UV spectroscopy, gel electrophoresis and viscosity measurements. Ni (H2N-C6H4COO) 2· 2H2O and Cd (H2NC6H4COO) 2· 3H2O complexes exhibit interaction activities with DNA. The experimental results indicate that the complexes can bind to DNA via an intercalative mode. The intrinsic binding constants of the complexes with genomic DNA are 5.2× 105-2.49× 105 M-1, respectively. |
| Anahtar Kelimeler |
| Cadmium(II) | DNA binding | Gel electrophoresis | Nickel (II) | P-Aminobenzoic acid |