| Yazarlar |
Eray ATALAY
Kafkas Üniversitesi, Türkiye |
Gökhan Bilgehan
Türkiye |
|
Pınar Şişman
Türkiye |
Halil İbrahim ERDOĞDU
Kafkas Üniversitesi, Türkiye |
| Özet |
| Objectives: In recent years, many effects of vitamin D except on bone metabolism have been discovered.Vitamin D contributes to the correction of the anemia by acting on the erythroid precursors in the bone marrowvia Vitamin D Receptor and provides the elimination of free radicals and prooxidant substances secondary toiron deficiency due to its antioxidant effect in iron deficiency anemia (IDA).Methods: A total of 97 female premenopausal women aged 18-44 were included in the study. Fifty patientswith hemoglobin levels below 12 mg/dl and iron deficiency were classified as IDA group, and 47 subjectswith hemoglobin levels of 12 mg/dl and above were classified as control group. The demographic data andbiochemical parameters of all patients included in the study were analyzed.Results: The vitamin D of the patient group was found to be 7.87 ± 3.63 ng/ml and the vitamin D of the controlgroup was 11.84 ± 6.72 ng/ml. The difference between the groups was statistically significant. There was apositive correlation between serum vitamin D and serum hemoglobin, hematocrit, serum MCH, serum ironlevel, transferrin saturation index, ferritin.Conclusions: In the light of the results of our study and other studies in the literature, we think that vitamin Ddeficiency may be important in patients with IDA and that vitamin D deficiency in these individuals willcontribute to the regulation of anemia due to positive effects of vitamin D on both erythropoiesis and hepcidinin IDA are considered. However, larger studies are needed to clarify this issue. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale |
| Dergi Adı | The European Research Journal |
| Dergi ISSN | 2149-3189 |
| Dergi Tarandığı Indeksler | TR DİZİN |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2020 |
| Cilt No | 6 |
| Sayı | 3 |
| Sayfalar | 232 / 237 |
| Doi Numarası | 10.18621/eurj.476438 |
| Makale Linki | https://dergipark.org.tr/en/doi/10.18621/eurj.476438 |
| Atıf Sayıları | |
| TRDizin | 1 |
