Evaluation of serum vitamin D levels in premenopausal women with iron deficiency anemia
Yazarlar (4)
Doç. Dr. Eray ATALAY
Kafkas Üniversitesi, Türkiye
Gökhan Bilgehan
T.C. Sağlık Bakanlığı, Türkiye
Pınar Şişman
T.C. Sağlık Bakanlığı, Türkiye
Prof. Dr. Halil İbrahim ERDOĞDU
Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
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| Dergi Adı | The European Research Journal | ||
| Dergi ISSN | 2149-3189 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2020 |
| Cilt / Sayı / Sayfa | 6 / 3 / 232–237 | DOI | 10.18621/eurj.476438 |
| Makale Linki | https://dergipark.org.tr/en/doi/10.18621/eurj.476438 | ||
| Özet |
| Objectives: In recent years, many effects of vitamin D except on bone metabolism have been discovered.Vitamin D contributes to the correction of the anemia by acting on the erythroid precursors in the bone marrowvia Vitamin D Receptor and provides the elimination of free radicals and prooxidant substances secondary toiron deficiency due to its antioxidant effect in iron deficiency anemia (IDA).Methods: A total of 97 female premenopausal women aged 18-44 were included in the study. Fifty patientswith hemoglobin levels below 12 mg/dl and iron deficiency were classified as IDA group, and 47 subjectswith hemoglobin levels of 12 mg/dl and above were classified as control group. The demographic data andbiochemical parameters of all patients included in the study were analyzed.Results: The vitamin D of the patient group was found to be 7.87 ± 3.63 ng/ml and the vitamin D of the controlgroup was 11.84 ± 6.72 ng/ml. The difference between the groups was statistically significant. There was apositive correlation between serum vitamin D and serum hemoglobin, hematocrit, serum MCH, serum ironlevel, transferrin saturation index, ferritin.Conclusions: In the light of the results of our study and other studies in the literature, we think that vitamin Ddeficiency may be important in patients with IDA and that vitamin D deficiency in these individuals willcontribute to the regulation of anemia due to positive effects of vitamin D on both erythropoiesis and hepcidinin IDA are considered. However, larger studies are needed to clarify this issue. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| TRDizin | 1 |